Tuesday, November 30, 2021

World AIDS Day 2021: All you need to know about vaccines for HIV and their development

World AIDS Day is observed on 1 December every year to show support for people living with Human Immunodeficiency Virus (HIV), to end inequalities that lead to AIDS and to fight social stigmas created around HIV.

Identified in 1981 for the first time, HIV has claimed around 36 million lives till now and is one the deadliest public health issues. Till now, no effective cure of HIV exists and once a person gets infected, they have the infection for life. Currently, there is also no vaccine available for HIV that can prevent or treat the virus.

How do vaccines work?

Initially, a vaccine is developed after research in a laboratory and is tested on volunteers after Phase I and Phase II trials of the vaccine are carried out safely among volunteers in the laboratory.

Since, vaccines have always been proved to be the most effective means to prevent an infectious disease, the need for an HIV virus is paramount as it could save millions of lives.

Vaccines are made from small amount of weak or dead germs and help the immune system to fight infections effectively.

What is the present status of research on HIV vaccines?

The US-based National Institutes of Health is conducting research to deliver an HIV preventive vaccine and two vaccine trials called Mosaico and Imbokodo will be conducted in clinical research sites in North America, South America and among HIV negative women of sub-Saharan Africa.

Since the year 1987, more than 30 HIV candidate vaccines have been tested in countries such as United Kingdom, China, Brazil, Thailand, Cuba and many more. The results of these vaccine trials have led to information that can aid in making better vaccines.

Treatment for HIV such as Anti-retroviral therapy or ART has helped in suppressing the virus and many people have lived a long life. Other drugs such as Pre-exposure Prophylaxis (PrEP) is also taken by HIV negative patients who are at a risk of contracting the infection.

However, an effective vaccine to help people from getting infected is still not available.

Recently, a team of researchers at Japan’s National Institute of Biomedical Innovation, Health and Nutrition, have claimed that they successfully eliminated the HIV virus in monkeys by inoculating a new vaccine and then injecting a processed HIV virus in the monkey. The researchers have said that they hope to begin clinical trials on humans within a period of five years.

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World AIDS Day 2021: Precautions to prevent transmission of HIV while engaging in sexual activity

World AIDS Day is observed on 1 December every year to raise awareness about Human Immunodeficiency Virus (HIV) which is a major public health issue. The day was first observed in the year 1988 and is an opportunity for people to unite in fighting against the virus, supporting those living with HIV, and knowing facts on how to protect themselves.

Some common ways through which HIV spreads are unprotected sex (sex without a condom or HIV medicine) or through sharing a piece of injection equipment with an HIV-positive patient.

If you are living with HIV, you can engage in sexual activity by taking precautions to prevent transmission through these methods:

  • Ensure to get regular check-ups and begin your treatment for HIV. Taking Anti-retroviral therapy help to reduce infection levels in the body. Also keep a check of Sexually transmitted diseases (STDs) by monitoring your penis and vaginal discharges.
  • Talk to your partner and tell them about the situation. Ensure that both of you take necessary precautions.
  • Using a latex male or female condom is effective in preventing both HIV transmission and STDs. However, abstinence is the only 100 percent effective way to prevent sexual transmission.
  • Drugs such as Pre-exposure prophylaxis can be taken by people who are HIV negative, in order to reduce the risk of contracting HIV. Post-exposure prophylaxis is another drug that can be consumed to reduce the risk of infection after exposure. The drug has to be taken within 72 hours of the exposure.
  • HIV does not spread through touching, through urine or through saliva. Oral sex, masturbation and erogenous play are other sexual methods that carry little to no risk of HIV transmission.
  • There is a very low risk of contracting HIV through oral sex, but in order to make it safer and avoid getting the bacterial infection in the mouth, always use a latex barrier such as a non-lubricated condom or a dental dam.
  • Cuts and abrasions near vaginas, rectums and the penis can cause the virus to enter one's body. Hence, keep a proper check on them too and avoid intercourse if there is a risk. Barrier methods such as damns and condoms along with using lube can reduce the risk of cuts around sensitive areas.
  • Use water-based lubes instead of oil lubes because it can result in condom ripping or a condom tear.
  • Remember to consult a doctor for your problems and talk to them about prevention methods.


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World AIDS Day 2021: Some medical and non-medical treatments to help HIV positive patients

Every year, 1 December is observed as World AIDS Day in order to increase awareness around Human Immunodeficiency Virus (HIV) epidemic, to speak against its stigma, and to draw attention to the failures that have led to making HIV a global health crisis.

HIV attacks the immune cells of our body, making the body vulnerable and increasing the risk of contracting other diseases. It can spread from one person to another through contact with certain bodily fluids of a person. Untreated HIV can lead to Acquired Immunodeficiency Syndrome (AIDS).

There is no effective cure of HIV till now, but several medical and non-medical treatments have proved to be helpful to HIV patients. Here are some treatment methods to follow if one is diagnosed with the infection-

Medical Treatment

Antiretroviral Therapy (ART) is the medicine taken for HIV treatment. The medicine helps in lowering the amount of HIV infection in the blood, also known as viral load.

Medical treatment of HIV involves keeping the viral load low in the body, along with checking that the CD4 cell count is high. The suppression of viral load means having less than 200 copies of HIV in per milliliter of blood.

Regular check-ups and proper intake of medicines will help in detecting HIV copies in the blood. If the copies reach below the 200-milliliter count, it means that the HIV treatment is working.

Taking medicines for HIV can lead to side effects also, such as nausea, fatigue and diarrhea. These side effects can be combated by consulting your health care provider regarding the issue and taking nutrient pills to boost immunity.

Complementary and Alternative Medicine (CAM):

These medications or therapies can be used in combination with medical treatment to counter HIV conditions. Yoga, massage therapies and meditation have proved to be effective in treating overall feelings of anxiety and depression in HIV patients.

Research has also found that acupuncture, the medical practice of placing needles onto various pressure points of the body, can also release body chemicals and give relief in pain.

Many HIV patients take milk thistle, a herb used to improve liver functions, as it does not interact with antivirals. However, there has been no concrete evidence that herbal medicines can reduce HIV symptoms.

Supplements are an essential part of HIV treatment since they support the immunity system. Calcium and Vitamin D improves bone health whereas fish oil helps in cholesterol reduction. Vitamin B-12 supplements are taken by pregnant women suffering from HIV and soy proteins are also taken to help in covering weight loss. Tablets of the mineral selenium can also be taken to improve metabolic functions of the body and to slow HIV progression.



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World AIDS Day 2021: All you need to know about antiretroviral therapy and how it works

Every year on 1 December, World AIDS Day is marked to create and raise awareness about Human Immunodeficiency Virus (HIV). According to data provided by the Indian government, HIV infection was first spotted in the year 1986 among female sex workers in Chennai.

During that time, it was considered to be a deadly disease as it had no cure, but today people suffering with HIV can lead a normal life with the help of antiretroviral therapy (ART).

What is antiretroviral therapy or ART?

ART is a primary treatment for HIV, however, not a complete cure for the infection. It is a ‘drug cocktail’ where patients suffering from HIV have to take a combination of up to seven antiretroviral drugs depending upon the viral load of the disease every single day. Furthermore, as per the World Health Organization (WHO) ART helps in reducing the risk of transmitting HIV.

ART Treatment:

Through Anti-retroviral therapy, patients effectively overpower the HIV replication that takes place in the body. If this therapy is done at the right time, it will restore the immune system as well as halt onset and progression of the disease. With the right medication at the right time, patients will enhance both quality of life and longevity, while reducing their chances of contracting opportunistic infections.

If any patient follows irregularity in its pattern in this treatment, then it can lead to resistance to HIV drugs resulting in weakening its effect. Currently, ART is available to those who need it. Additionally, public health facilities across the country are directed to ensure that ART is provided to people living with HIV/AIDS (PLHA). Also, special attention is given to women and infected children who suffer from the treatment of sero-positives.

Importance of ART In India:

There are around 544 Care and Support Centres (CSCs) in India who help in improving the number of people adhering to the treatment, as per the 2018-19 Annual Report of the National Aids Control Organisation (NACO). However, as per data by the News Minute, only 50 percent of the 2.1 million HIV+ patients in the country were availing the treatment.

NACO had updated its guidelines in 2017 for ART, making it necessary for every person testing positive for HIV to be put on the treatment, regardless of their CD4 count. For the unversed, a normal CD4 count is from 500 to 1,400 cells per cubic millimetre of blood. However, CD4 counts reduce over time especially in people who are not receiving ART.

So, with the help of these ART centres, services including ART, CD4 counts, along with psychosocial support, referrals to social benefit stigma and schemes are held.



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World AIDS Day 2021: From how it is caused to risk factors, all you need to know about disease,

Every year on 1 December, World AIDS Day is marked and observed to raise awareness as well as unite people in the fight against the global health issue of Acquired immunodeficiency syndrome (AIDS) related illness. Along with the illness, people and groups also are fighting against the stigma surrounding the disease.

Furthermore, the aim of this day is to focus on providing support and care to those who are already living with the disease.

What is AIDS and how is it caused?

AIDS is the most advanced stage of HIV which stands for human immunodeficiency virus. It is a virus that breaks down certain cells in the immune system. AIDS is caused by life-threatening HIV which attacks the immune system of the patient and drastically reduces the body’s resistance to other illnesses.

Additionally, this disease serves as the final stage for people who live with HIV. However, with the right medical treatment and timely care, HIV positive patients can continue to live a healthy life.

Below are some of the groups who are most at risk of becoming infected with HIV:

- People having a current or a previous partner who has been diagnosed with HIV

- People share equipment such as syringes or inject drugs

- People with a history of sexually transmitted infections, Hepatitis C or Hepatitis B

- Babies born from a parent who has HIV and has not taken timely treatment for it

- People who have unprotected sex

- People who share sex toys with someone infected with HIV

Theme this year:

The theme for World AIDS Day this year is “End inequalities. End AIDS”. The main objective of this theme is to focus on patients and people who are left behind and not taken care of. Furthermore, the World Health Organization (WHO) and its partners will also highlight the growing inequalities in access to essential HIV services.

History and significance:

In August 1988, World AIDS Day was first designated by James W. Bunn and Thomas Netter. They wanted to get some impression of control over the pandemic that had claimed the lives of so many people during that time. For the unversed, both Bunn and Netter were public information officers of the WHO for the AIDS Global Program.

Bunn and Netter conveyed and carried the idea for the observation of this day to the Director of the program, Dr Johnathan Mann. Following this, Mann approved the day for 1 December, which still remains significant.

Advancements in medical science have made significant improvements for people living with HIV, especially since the 1990s. However, due to the ongoing coronavirus pandemic and lockdown in various parts of the world, HIV prevention, testing and treatment have all taken a blow.



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African lion plays tug-of-war with tourists on a safari ride; video goes viral, watch here

A tourist group from South Africa was in for the biggest surprise of their lives when a lion came to help their safari vehicle, which was stuck in the middle of a ditch.

The incident took place in the Klaserie Private Nature Reserve Part of Kruger National Park, South Africa. And, now the clip of the African lion helping the group and tugging playfully at a rope has gone viral on the Internet. 

The Baobab Ridge Game Lodge was conducting a tour headed by tour leader, Jabulani Salinda. The group was going through the Baobab Ridge when the safari vehicle got stuck in a jungle trail.  The group was well prepared for such conditions and they took out a tow rope to bail them out from the situation. 

The tow rope was then attached to the vehicle for rescue purposes but to everyone’s surprise, a lion appeared near the rope and began to tug at the rope. The lion grabbed the rope in its teeth and initiated a tug of war, as the jeep tried to move forward. The video was shared by the Baobab Ridge Game Lodge on their Facebook page.

Watch the hair-raising video here.

In the clip, the lion can be seen tugging at the rope and also trying to wrap it around a tree in an attempt to stop the safari from going forward. It also follows the safari till a certain distance while grabbing the rope in its teeth.

Some users found the clip amusing while several others expressed security and safety concerns regarding the tourists who were on the tour and felt that it was a reckless move by the tourist company.

The tourist company has given an explanation for the incident in a Facebook post and said that the guide could not get down as the lion had appeared and neither could he remove the rope. Hence Salinda, the guide, tried his best to move away from the lion along with keeping in mind not to provoke the animal in fear of initiating a chase.

Meanwhile, Salinda told the New York Post that the group was worried about seeing the lion and he tried to calm them. He said that initially they felt that the lion was angry but it was only a few moments later when they realised that the lion was playing.  Everyone then enjoyed the fearless feline’s tug-of-war and it was for the first time in his career of 19 years that Salinda had seen a lion play this way.

 



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Monday, November 29, 2021

Omicron: A layman's guide to understand COVID-19 variants and strains

A new coronavirus variant was detected in South Africa by scientists on 24 November. Classified as the highly-transmissible “variant of concern”, the now-named Omicron has caused panic across the world with many nations shutting their doors in a flashback to the early days of the outbreak of the pandemic. But how is a variant of concern different from a variant of consequence or even variant of interest. Let's find out:

What are variants?

Remember Loki, how there were many Lokis but none of them looked the same? In this case, experts say, to spread, a virus needs to infect a host, replicate and produce copies of itself. But when a virus replicates it does not always manage to produce an exact copy of itself. This means that, over time, the virus may start to differ slightly in terms of its genetic sequence. Any changes to the viral genetic sequence during this process is known as a mutation and viruses with new mutations are sometimes called variants. Variants can differ by one or multiple mutations.

When a new variant has different functional properties to the original virus and becomes established in a population, it is sometimes referred to as a new strain of the virus. In short, all strains are variants, but not all variants are strains.

Classification of variants

Scientists monitor all variants but may classify certain ones as Variants Being Monitored, Variants of Concern, Variants of Interest or Variants of High Consequence.

Image Coutesy: AFP

A Variant Being Monitored is one that has developed specific genetic markers associated with changes that reduce the effectiveness of antibodies generated against previous infection or vaccination, reduce efficacy of treatments, or increase transmission or disease severity. Variants Being Monitored have been observed or demonstrated the potential to decrease the effectiveness of approved or authorised vaccines or therapies — or have been associated with more severe disease or higher transmission, but no longer pose an immediate or significant risk to public health.

Image Courtesy: WHO

A variant with specific genetic markers that have been associated with changes to receptor binding, reduced neutralisation by antibodies generated against previous infection or vaccination, reduced efficacy of treatments, potential diagnostic impact, or predicted increase in transmissibility or disease severity is classified as Variant of Interest.

Image Courtesy: WHO

A variant for which there is evidence of an increase in transmissibility, more severe disease (eg, increased hospitalisations or deaths), significant reduction in neutralisation by antibodies generated during previous infection or vaccination, reduced effectiveness of treatments or vaccines, or diagnostic detection failures categorised as Variants of Concern. Omicron has joins Delta, Alpha, Beta and Gamma on the current WHO list of Variants of Concern.

Image Courtesy: WHO

A Variants of High Consequence has clear evidence that prevention measures or medical countermeasures (MCMs) have significantly reduced effectiveness relative to previously circulating variants.

With input from agencies

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As world closes its doors on African nations over Omicron COVID-19 variant, India extends a helping hand

The Omicron COVID-19 variant has sparked fears across the world with countries across the globe scrambling to prevent it from spreading any further. Several countries have announced flight bans affecting seven African nations, while others, including India, have tightened measures to avoid a further outbreak.

In this type of environment, India has once again stepped up and offered its support to the countries affected in Africa.

The move was lauded by many, including England batting legend Kevin Pietersen. He lauded India’s move on Twitter.

What is India doing to help Africa?

As the World Health Organisation designated Omicron as a “variant of concern”, India on Monday said that it expressed their solidarity with the countries, particularly in Africa, who have so far been affected by the Omicron variant.

The government announced plans to supply Made-in-India vaccines through COVAX or bilaterally.

A statement released by the Ministry of External Affairs on 29 November said that the central government has cleared all orders placed so far by COVAX for supplies of Covishield vaccines including to African countries such as Malawi, Ethiopia, Zambia, Mozambique, Guinea and Lesotho.

The statement also added, "India also stands ready to supply essential life-saving drugs, test kits, gloves, PPE kits and medical equipment such as ventilators, as may be required."

As of date, India has supplied more than 25 million doses of Made-in-India vaccines to 41 countries in Africa, including nearly one million doses as grant to 16 countries and more than 16 million doses under the COVAX facility to 33 countries.

India resumed export of COVID-19 vaccines under its ‘Vaccine Maitri’ programme in early November. The initiative started up again after a seven month pause when India was struggling to get its population vaccinated.

Under the scheme, Bangladesh, Myanmar, Nepal, Bhutan, Maldives, Mauritius, Sri Lanka, Brazil, Morocco, South Africa, Afghanistan, Mexico, DR Congo, Nigeria and the United Kingdom have received vaccine doses from India.

China’s helping hand

India’s announcement of extending a helping hand came after President Xi Jinping said China would offer another one billion doses of COVID-19 vaccines to African countries.

The pledge of the additional vaccine doses is on top of the nearly 200 million that China has already supplied to the continent.

Xi said that his country would donate 600 million doses directly. A further 400 million doses would come from other sources, such as investments in production sites.

“We must continue to fight together against COVID,” Xi was quoted as saying on Monday. “We must prioritise the protection of our people and close the vaccination gap."

Africa’s poor vaccination rates

The Omicron variant of the coronavirus infection is just another hurdle for Africa, which is already battling with poor vaccination rates.

On 1 October, the WHO reported that the overall figure for those fully vaccinated is only 4.4 percent, compared to the European Union which has seen around 62 percent of its population fully vaccinated.

Moreover, the WHO had said that only 15 of the 54 countries had achieved the target of vaccinating 10 percent of its population by end of September.

According to reported information, Africa today has only vaccinated around 7 percent of its population.

Experts note that the emergence of the new variant has brought into sharp focus the consequences of global vaccine inequity as well as the discriminatory practices that have been directed at southern African countries.

Dr Richard Hatchett, CEO of CEPI, one of the groups behind the UN-backed COVAX shot-sharing initiative, was quoted as telling The Associated Press , "The virus is a ruthless opportunist, and the inequity that has characterised the global response has now come home to roost."

The COVAX vaccine sharing programme was supposed to address the inequality, but it has fallen woefully short.

With inputs from agencies

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Omicron challenge for pharmas as race to make vaccines effective begins again

‘Will my vaccine work against the new COVID-19 variant, Omicron , is the question that almost everyone is asking.

With the World Health Organisation in its latest update stating that the new variant poses a “very high” risk globally, countries are not only closing their doors to travellers from high risk countries, but also asking their citizens to get vaccinated.

However, the question that still needs to be answered is whether the strain that's considered to be highly infectious will evade vaccines.

We try to delve deeper on the issue and give you answers.

What we know of the Omicron variant so far?

As of now what scientists have found is that the variant may be more transmissible and better able to evade the body's immune responses.

Experts have said that as of now what they have studied is that in the Omicron variant the spike protein has more than 30 mutations. Ten of these mutations have been seen in what is called the receptor-binding domain or RBD of the spike protein. The RBD is that part of the spike protein which latches onto a human cell. A highly mutated RBD can carry the Omicron variant undetected by the body’s immunity.

Cardiff University’s immunologist Prof Paul Morgan speaking to The Guardian said that although the Omicron variant looks more infectious “a blunting rather than a complete loss [of immunity] is the most likely outcome”.

“The virus can’t possibly lose every single epitope (areas on the virus which antibodies and T cells can target) on its surface, because if it did that spike protein couldn’t work anymore. So, while some of the antibodies and T cell clones made against earlier versions of the virus, or against the vaccines may not be effective, there will be others, which will remain effective.”

So, will vaccines work against Omicron?

Scientists keep repeating this point and we have to pay attention: Vaccines are effective, but DO NOT offer 100 percent protection.

In the case of the new variant, this probably holds true too, though experts are still studying it.

Comparing it to the Delta variant could be helpful in understanding if vaccines are indeed effective against it. In the case of the Delta variant, COVID-19 patients were reported to have nine times less likely to die. Fully vaccinated people were also said to have three times lower chances of catching infection compared to those unvaccinated.

Hence, the real worry remains for those unvaccinated. They don’t have natural or vaccinated immunity against the Omicron variant.

India's top bio-medical scientist Dr Gagandeep Kang also explained how vaccinated individuals were relatively safer from the variant. She said that data showed individuals who contracted the infection and were later vaccinated, were either asymptomatic or had mild infection after contracting 'Omicron'.

Greater transmissibility doesn't necessarily mean greater severity, she added.

"Fortunately, in India, we have a small advantage because a lot of our people were infected before they were vaccinated. And we know that a combination of vaccination and infection gives you the broadest possible immune response. So, we may be lucky there," she was quoted as telling NDTV.

What do vaccine makers say?

Vaccine makers have already responded to the new variant. In the case of Pfizer, the US drug giant has said that they have already started working on a version of its COVID-19 vaccine specifically targeting the 'Omicron' variant.

Pfizer's CEO Albert Bourla said that they had begun testing the current vaccine against the 'Omicron' variant.
"I don't think the result will be the vaccines don't protect," Bourla said.

But the testing could show that existing shots "protect less," which means "that we need to create a new vaccine," Bourla said.

"Friday we made our first DNA template, which is the first possible inflexion of the development process of a new vaccine," he said.

German vaccine maker BioNTech also on Monday announced that it had started developing a new COVID-19 vaccine that aims to combat the Omicron variant.

The German company, which partners with Pfizer on COVID-19 vaccines, initiated "the development of an adapted vaccine" for Omicron to allow it to "move forward quickly."

Moderna in a statement on Sunday that it expects to have a new version of its shot available by early 2022, and that it should know whether its current vaccine has sufficient protection in the next two weeks.

Moderna’s Chief Medical Officer Paul Burton speaking to BBC’s 'Andrew Marr Show' said that if they had to “make a brand new vaccine I think that’s going to be early 2022 before that’s really going to be available in large quantities”.

Johnson & Johnson is also evaluating the effectiveness of its COVID-19 vaccine against Omicron, while also pursuing a vaccine specific to the variant.

"We have begun work to design and develop a new vaccine against Omicron and will rapidly progress it into clinical studies if needed," Mathai Mammen, global head of research for J&J's pharmaceuticals unit was quoted as saying to Business Today.

Similarly, Novavax Inc has also started working on a version of its COVID-19 vaccine to target the Omicron variant and would have the shot ready for testing and manufacturing in the next few weeks.

With inputs from agencies

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How Vladimir Putin’s visit will bring India and Russia closer despite New Delhi’s deepening ties with US

Addressing the Primakov Institute of World Economy and International Relations in Moscow in July this year, External Affairs Minister S Jaishankar stated, “Relations between Russia and India have been amongst the steadiest of the major relationships in the world after the Second World War. The paradox though is that precisely because it has held so steady, this relationship is sometimes taken for granted.”

He added, “Ours is a particularly mature relationship. More than its contemporaries, it has withstood the test of time, finding new convergences with changing circumstances.” Indo-Russian relations have grown over the years.

Prime Minister Narendra Modi and Russian President Vladimir Putin meeting 19 times since 2014 displays the steadfastness of the relationship. Russia displayed its proximity to India, when Putin participated in the Modi-chaired conference on maritime security of the UN Security Council, under India’s presidency. The upcoming summit would be their 20th meeting.

Historically, it was Soviet support that enabled India to free Bangladesh from the clutches of Pakistan in 1971 and kept the US and China at bay. Since then, Indo-Russian ties have remained steady. Russia has supported India in global forums, even when the Western world was pro-Pakistan. Similarly, India has never joined the world in criticism of Russia.

Though it is an established fact that India is now firmly in the US camp, yet its relations with Russia, a US adversary, remain steady. India and Russia are together in multiple forums including BRICS (Brazil, Russia, India, China and South Africa), RIC (Russia, India and China) and SCO (Shanghai Cooperation Organisation).

It is believed that Russia brought India into the SCO as a counterbalance to China, while China invited Pakistan for counterbalancing India. India also inducted Russia as a dialogue partner in the Indian Ocean Rim Association on 17 November. The group has 23 members and 10 dialogue partners. It gives Russia a major role in the Indian Ocean.

India and Russia are coordinating closely on the developing scenario in Afghanistan. The two nations are working in unison to prevent Afghanistan from becoming a terrorist hub and a major drug exporter. Both have similar concerns. It was Russia that provided the first opportunity for the Indian and Chinese foreign ministers to meet to commence diffusing the stalemate in Ladakh. This conversation was on the sidelines of the SCO summit in Moscow in September 2020.

Simultaneously, Russia-China relations are improving. With both nations being US adversaries, it is natural for them to be close allies. With the Western world discussing a diplomatic boycott of the Chinese Winter Olympics, Putin has accepted the Chinese invitation to attend the opening ceremony of the games, scheduled for February next year. China and Russia conduct joint exercises in the disputed South China Sea.

In a few cases, there are differing views between India and Russia. Russia views the Quad negatively. Russian Foreign Minister Sergey Lavrov is stated to have mentioned that the Quad was “directed at eroding long-standing universal formats of cooperation in the Asia-Pacific region that exist under the auspices of the association of Southeast Asian nations”.

On a visit to India in April this year, Lavrov mentioned to Jaishankar that military alliances in the region (implying Quad) would be counterproductive. He supported the Chinese view that Quad was directed against it. Jaishankar tweeted, “I shared (with Russian Foreign Minister) our viewpoint on the Indo-Pacific.” These differences have never let the relationship slide.

India is currently funding the Chennai-Vladivostok Eastern Maritime Corridor, which supplements the North-South Corridor through Iran. Simultaneously, there are discussions on the Northern Sea Route, in which both nations have special interests. The two nations have upgraded their relationship. The first 2+2 meeting, involving the foreign and defence ministers, is also scheduled to be held on 6 December.

As the Indian Ambassador to Moscow, D Bala Venkatesh Varma, stated in an interview last month, “India’s engagement is in line with Russia’s interests and is in line with India’s own interests; we have opened up new avenues of engagement whose impact will be measured not in terms of months or years but decades.”

India moved ahead with its procurement of the S-400 Triumf Missile Systems despite threats of sanctions from the US, the delivery for which is on schedule. India has defended its procurement on the basis that it was signed prior to CAATSA (Countering American Adversaries Through Sanctions Act) coming into force. The reality remains that India’s dependence on Russian military equipment cannot be ignored. Currently, 65 percent of Indian armed forces equipment is of Russian origin and India continues to rely on Russia for spares.

As Foreign Secretary Harsh Shringla had stated when discussing Indo-Russia relations, that without Russian spare parts and maintenance help, “our ships won’t sail, our planes won’t fly”. India has signed a $3-billion deal to lease a Russian nuclear powered Akula Class submarine, likely to be delivered by 2025. In a recent decision, the defence ministry cleared the procurement of 7.5 lakh AK-203 assault rifles deal with Russia, which will be manufactured in Amethi at a cost of Rs 5,000 crore. Another major military concern for India is Russia not providing equipment currently in service in India to Pakistan. Thus, despite everything, India has to maintain close ties with Russia. India also participates in every major Russian exercise.

The only area where Indo-Russian relations have not been progressing is bilateral trade. In 2019-20, the trade between the two countries was $10.11 billion, well below desired levels. The two countries have set a trade target of $30 billion by 2025. Negotiations for the India-Eurasian Economic Union (EAEU) Free Trade Agreement, which could boost trade, commenced in August last year.

The forthcoming India-Russia summit is on 6 December. In this summit, a logistics support pact between the armed forces of the two countries, on similar lines as between India and the US as also with Japan, is expected to be inked. In addition, a number of trade and technology agreements will be signed. The upcoming visit, though short and among the few by Putin since the pandemic took hold, would only draw the nations closer. Minor differences, which cropped up due to India’s strategic shift and closer alliance with the US, would be put to rest.

The author is a former Indian Army officer, strategic analyst and columnist. Views expressed are personal.​

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How Valdimir Putin’s visit will bring India and Russia closer despite New Delhi’s deepening ties with US

Addressing the Primakov Institute of World Economy and International Relations in Moscow in July this year, External Affairs Minister S Jaishankar stated, “Relations between Russia and India have been amongst the steadiest of the major relationships in the world after the Second World War. The paradox though is that precisely because it has held so steady, this relationship is sometimes taken for granted.”

He added, “Ours is a particularly mature relationship. More than its contemporaries, it has withstood the test of time, finding new convergences with changing circumstances.” Indo-Russian relations have grown over the years.

Prime Minister Narendra Modi and Russian President Vladimir Putin meeting 19 times since 2014 displays the steadfastness of the relationship. Russia displayed its proximity to India, when Putin participated in the Modi-chaired conference on maritime security of the UN Security Council, under India’s presidency. The upcoming summit would be their 20th meeting.

Historically, it was Soviet support that enabled India to free Bangladesh from the clutches of Pakistan in 1971 and kept the US and China at bay. Since then, Indo-Russian ties have remained steady. Russia has supported India in global forums, even when the Western world was pro-Pakistan. Similarly, India has never joined the world in criticism of Russia.

Though it is an established fact that India is now firmly in the US camp, yet its relations with Russia, a US adversary, remain steady. India and Russia are together in multiple forums including BRICS (Brazil, Russia, India, China and South Africa), RIC (Russia, India and China) and SCO (Shanghai Cooperation Organisation).

It is believed that Russia brought India into the SCO as a counterbalance to China, while China invited Pakistan for counterbalancing India. India also inducted Russia as a dialogue partner in the Indian Ocean Rim Association on 17 November. The group has 23 members and 10 dialogue partners. It gives Russia a major role in the Indian Ocean.

India and Russia are coordinating closely on the developing scenario in Afghanistan. The two nations are working in unison to prevent Afghanistan from becoming a terrorist hub and a major drug exporter. Both have similar concerns. It was Russia that provided the first opportunity for the Indian and Chinese foreign ministers to meet to commence diffusing the stalemate in Ladakh. This conversation was on the sidelines of the SCO summit in Moscow in September 2020.

Simultaneously, Russia-China relations are improving. With both nations being US adversaries, it is natural for them to be close allies. With the Western world discussing a diplomatic boycott of the Chinese Winter Olympics, Putin has accepted the Chinese invitation to attend the opening ceremony of the games, scheduled for February next year. China and Russia conduct joint exercises in the disputed South China Sea.

In a few cases, there are differing views between India and Russia. Russia views the Quad negatively. Russian Foreign Minister Sergey Lavrov is stated to have mentioned that the Quad was “directed at eroding long-standing universal formats of cooperation in the Asia-Pacific region that exist under the auspices of the association of Southeast Asian nations”.

On a visit to India in April this year, Lavrov mentioned to Jaishankar that military alliances in the region (implying Quad) would be counterproductive. He supported the Chinese view that Quad was directed against it. Jaishankar tweeted, “I shared (with Russian Foreign Minister) our viewpoint on the Indo-Pacific.” These differences have never let the relationship slide.

India is currently funding the Chennai-Vladivostok Eastern Maritime Corridor, which supplements the North-South Corridor through Iran. Simultaneously, there are discussions on the Northern Sea Route, in which both nations have special interests. The two nations have upgraded their relationship. The first 2+2 meeting, involving the foreign and defence ministers, is also scheduled to be held on 6 December.

As the Indian Ambassador to Moscow, D Bala Venkatesh Varma, stated in an interview last month, “India’s engagement is in line with Russia’s interests and is in line with India’s own interests; we have opened up new avenues of engagement whose impact will be measured not in terms of months or years but decades.”

India moved ahead with its procurement of the S-400 Triumf Missile Systems despite threats of sanctions from the US, the delivery for which is on schedule. India has defended its procurement on the basis that it was signed prior to CAATSA (Countering American Adversaries Through Sanctions Act) coming into force. The reality remains that India’s dependence on Russian military equipment cannot be ignored. Currently, 65 percent of Indian armed forces equipment is of Russian origin and India continues to rely on Russia for spares.

As Foreign Secretary Harsh Shringla had stated when discussing Indo-Russia relations, that without Russian spare parts and maintenance help, “our ships won’t sail, our planes won’t fly”. India has signed a $3-billion deal to lease a Russian nuclear powered Akula Class submarine, likely to be delivered by 2025. In a recent decision, the defence ministry cleared the procurement of 7.5 lakh AK-203 assault rifles deal with Russia, which will be manufactured in Amethi at a cost of Rs 5,000 crore. Another major military concern for India is Russia not providing equipment currently in service in India to Pakistan. Thus, despite everything, India has to maintain close ties with Russia. India also participates in every major Russian exercise.

The only area where Indo-Russian relations have not been progressing is bilateral trade. In 2019-20, the trade between the two countries was $10.11 billion, well below desired levels. The two countries have set a trade target of $30 billion by 2025. Negotiations for the India-Eurasian Economic Union (EAEU) Free Trade Agreement, which could boost trade, commenced in August last year.

The forthcoming India-Russia summit is on 6 December. In this summit, a logistics support pact between the armed forces of the two countries, on similar lines as between India and the US as also with Japan, is expected to be inked. In addition, a number of trade and technology agreements will be signed. The upcoming visit, though short and among the few by Putin since the pandemic took hold, would only draw the nations closer. Minor differences, which cropped up due to India’s strategic shift and closer alliance with the US, would be put to rest.

The author is a former Indian Army officer, strategic analyst and columnist. Views expressed are personal.​

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Gunshot victim meets medical student who saved his life 25 years ago in US

In a heart-warming incident, a man, who was shot 25 years ago finally got to thank a doctor who saved his life. It was an emotional reunion between the gunshot victim, Damon Walker, and the doctor, Michael Franks, who saved him after the Baltimore resident was shot in the year 1996.

A video of the reunion captures Walker meeting Dr Frank, who was a medical student at University of Maryland when the incident took place. It was Walker’s wish to thank Dr Franks, who had helped him in the nick of time.
According to CNN, the duo talked, connected, and hugged when they met. Meanwhile, Franks asserted that they went and had lunch across the street while they got to know more about each other.

The fatal incident happened in the year 1996 on New Year’s Day, when Walker bumped into a robber who looted and shot him near Baltimore’s Hamburg Street Bridge. As he lay there bleeding, a car suddenly pulled up and a man reached out to help him, who wanted to give him immediate medical attention.

While speaking to WBAL, Franks explained that he was also leaving a celebration when he spotted a man bleeding on the side of the road. Before he could actually spot the injured man, he took a wrong turn that night that made him witness the incident and also become a good Samaritan. “I knew he was in trouble and he didn’t have 10 to 15 minutes for an ambulance to come,” he recalled. So, Franks carried Walker in his car and took him safely to the Shock Trauma centre which was a few minutes away.

However, it took 25 years for Walker to find the man who saved his life that fateful night. He and his mother finally found Franks after searching for him on the internet for years, as per news reports. Furthermore, a phone call to Franks made the reunion possible. Currently, he is a urologist at Virginia Urology. Till date, he was unaware of what happened to Walker or if he had survived the bullet, as he did not have any idea about him after he left the hospital.



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Solomon Islands violence recedes but underlying tension remains; is China to blame for unrest?

Violence receded Friday in the capital of the Solomon Islands, but the government showed no signs of addressing the underlying grievances that sparked two days of riots, including concerns about the country’s increasing links with China.

Prime Minister Manasseh Sogavare sought to deflect attention from domestic issues by blaming outside interference for stirring up the protesters, with a thinly veiled reference to Taiwan and the United States.

External pressures were a “very big ... influence. I don’t want to name names. We’ll leave it there,” Sogavare said.

Honiara’s Chinatown and its downtown precinct were focuses of rioters, looters and protesters who demanded the resignation of Sogavare, who has been prime minister intermittently since 2000.

Sogavare has been widely criticized by leaders of the country’s most populous island of Malaita for a 2019 decision to drop diplomatic ties with Taiwan in favor of mainland China. His government, meanwhile, has been upset over millions in US aid promised directly to Malaita, rather than through the central government.

Here’s a look at some of the reasons behind the turmoil:

Ethnic tensions open old wounds

The Solomon Islands are famous as a battleground of World War II, the pivotal Battle of Guadalcanal named after the country’ largest island where the restive capital Honiara is located.

It was then known as the British Solomon Islands Protectorate and became the Solomon Islands before independence in 1978. The South Pacific nation of 700,000 people — mostly Melanesian but also Polynesian, Micronesian, Chinese and European — is, like neighbouring Australia and New Zealand, a constitutional monarchy with Queen Elizabeth II the Head of State.

A migration of settlers from Malaita, the country’s second biggest island and most populous province, to the economic opportunities on Guadalcanal and Honiara stoked ethnic tensions and eventually unrest.

The South Pacific nation of 700,000 people is, like neighbouring Australia and New Zealand, a constitutional monarchy with Queen Elizabeth II the Head of State. Image courtesy: Google Maps

In the late 1990s, native Guadalcanal islanders, known as Guales, launched a campaign of violence and intimidation to drive the Malaitans off the island. The Malaita Eagle Force militia was formed to protect them in a conflict that led the government to declare a four-month state of emergency in 1999.

Australia and New Zealand rejected the government’s request for help. With the police force ethnically divided, law and order on Guadalcanal collapsed.

In 2000, the Malaita Eagle Force kidnapped Prime Minister Bartholomew Ulufa’alu, a Malaitan, because they did not consider he was doing enough for the Malaitans’ cause.

Ulufa’alu resigned in exchange for his freedom, and the current Prime Minister Manasseh Sogavare began the first of his four stints as the unstable nation’s leader.

What's China's role in the unrest?

China has provided another cause for the community to divide, with the government supporting Beijing and the Malatian leaders supporting Taiwan.

The self-ruled island of Taiwan split from mainland China after a civil war in 1949, but Beijing claims it as part of its territory and has persuaded all but 15 countries, most of them small and poor in Africa and Latin America, to switch recognition to the mainland.

But experts say the unrest on the Solomon Islands is driven by the same underlying causes that have undermined the social fabric for decades: inter-island and ethnic tensions, a perceived lack of sharing of resources between Guadalcanal and Malaita, widespread poverty and high youth unemployment.

“Geopolitical tensions have been the spark but not the major driver,” said Jonathan Pryke, Pacific Islands program director at the Lowy Institute international policy think tank.

“’I’m sure there is some degree of affection for Taiwan in Malaita, but it’s also another way for Malaitans to express their frustration at the national government,” he added.

Pryke said it was too soon to judge whether the Solomons would benefit financially from their 2019 switch in diplomatic relations to Beijing.

While Beijing’s financial inducements to cut ties with Taiwan have not yet borne fruit, the Solomons had closed its borders throughout the pandemic, which limited Chinese engagement.

Resentment against Chinese business people is longstanding on the Solomons and resulted in much of Honiara’s Chinatown being burned in 2006, and again this week.

“The Chinese communities are vulnerable in the Solomon Islands because they don’t have the traditional support base,” Pryke said. “They don’t have the tribes the families that would would given them some extra degree of cultural isolation from this sort of unrest.”

How did Australia become involved?

Australia and the Solomons signed their first bilateral security treaty in 2017. It provides a legal basis for the rapid deployment of Australian police, troops and associated civilians in the event of a major security challenge.

Australian police were in the air aboard a military transport plane within hours of Sogavare invoking the treaty on Thursday.

Australia had led a force of Pacific Islands police and troops under the Regional Assurance Mission to Solomon Islands, or RAMSI, from 2003 to 2017. It included 2,300 police and troops from 17 nations, invited by the Solomons’ government. The deployment successfully ended the conflict that killed 200 people.

In the five years of ethic and civil unrest before RAMSI arrived, the Solomons was close to becoming a failed state.

The bilateral treaty acknowledges that underlying causes of the unrest remained and posed development challenges.

“The Solomon Islands will need ongoing support to retain the gains made under RAMSI and to help build long-term stability and enduring growth,” the Australian government said in 2017.



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Iran nuclear talks resume: What are the prospects for dialogue? Can world powers curb Tehran?

Can the landmark 2015 nuclear deal between Iran and world powers be restored? As Iran and six global powers gather in Vienna Monday to discuss the tattered treaty, the answer appears to be no.

Since then president Donald Trump withdrew from the agreement in 2018, Iran has raced forward with its nuclear programme, making it all but impossible to simply turn back the clock. The election of a hard-line leader in Iran, coupled with a US administration seen as weak in the region, have further dampened prospects for a breakthrough.

Former Israeli defence minister Moshe Yaalon, who fiercely opposed the original deal, was one of the rare Israeli voices to argue against withdrawal at the time. He now says the US pullout has turned out to be the “main mistake” in the region of the past decade.

A flawed deal, he told a security conference last week, “probably was better than not having the agreement and to allow the Iranians to use the withdrawal as an excuse to go ahead with the project.”

“Now they are in the closest stage they have been ever to become a (nuclear) threshold State,” he said.

Here’s a closer look at the deal and what to expect this week:

What is the deal they're talking about?

The original deal, known as the Joint Comprehensive Plan of Action, or JCPOA, was agreed after then Iranian president Hassan Rouhani, widely seen as a moderate, first took office.

In 2015, Iran signed an agreement with the US, Russia, China, Germany, France and Britain that was intended to set limits on Tehran’s nuclear programme in order to block it from building a nuclear weapon — something it insists it doesn’t want to do.

In exchange, Iran received relief from sanctions that those powers had imposed, including on its exports of oil and access to the global banking system. Iran was allowed to continue to pursue its nuclear programme for civilian purposes, with strict limits on how much uranium it could enrich, the purity it could enrich it to and other measures.

Before the deal, conservative estimates were that Iran was within five to six months of being able to produce a bomb, while some feared it was within two to three months. With the deal safeguards in place, that “breakout time” was estimated to be more than a year.

Why did it collapse?

Critics, led by then Israeli prime minister Benjamin Netanyahu, assailed the deal because the restrictions on Iran were temporary. They also complained it did not address Iran’s non-nuclear military activity, such as its support for hostile militant groups and development of long-range missiles.

In 2018, then president Donald Trump pulled the US unilaterally out of the deal, criticizing clauses that ease restrictions on Iran in stages — and also the fact that eventually the deal would expire and Iran would be allowed to do whatever it wanted with its nuclear technology. He also said it needed to be renegotiated to address Iran’s ballistic missile program and regional influence such as backing militant groups.

When Trump withdrew, with strong urging from Netanyahu, he promised a campaign of “maximum pressure” on Iran. However, the approach appears to have backfired. Despite increased US sanctions, Iran’s government remains firmly in power, and the country has raced forward with nuclear research banned by the original deal.

Can't the deal just be reinstated?

The crippling American sanctions that followed took their toll on Iran’s economy — but failed to bring Tehran back to the table to broaden the deal as Trump wanted. Instead, Tehran steadily exceeded the limitations set by the deal to pressure the remaining members for economic relief.

Iran began exceeding the limits of the agreement after the US withdrawal, and now enriches small amounts of uranium up to 60 percent purity — a short step from weapons-grade levels of 90 percent. Iran also spins advanced centrifuges once barred by the accord and its uranium stockpile now far exceeds the accord’s limits.

Iran in February began restricting International Atomic Energy Agency inspections of its nuclear facilities. Instead, it said that it would preserve surveillance footage of the facilities for three months and hand them over to the IAEA if it is granted sanctions relief. Otherwise, Iran said it would erase the recordings.

For Iran to return to the deal, it must revert to enriching uranium to no more than 3.67 percent purity, stop using advanced centrifuges and drastically reduce how much uranium it enriches, among other things.

Experts say that even if Iran were forced to give up its uranium stockpile or halt its research, the expertise it has gained cannot be taken away.

What are the prospects for this week's talks?

In the short term, it does not look encouraging. Heading into the talks, Iran’s hard-line president, Ebrahim Raisi, has made maximalist demands, including calls for the US to unfreeze $10 billion in assets as an initial goodwill gesture.

The tough line might be an opening gambit. European negotiators remain confident a deal will be reached in the short to medium term.

But US officials do not appear optimistic. President Joe Biden and his top advisers have held a series of meetings in recent weeks with key allies and negotiating partners to prepare for the possible failure of talks.

Because of Trump’s withdrawal, the Americans won’t even be in the negotiating room. Instead, they will be nearby and work through mediators.

In an interview broadcast Friday, chief US negotiator Rob Malley said signs from Iran “are not particularly encouraging.”

Speaking to NPR, he said the US prefers a diplomatic solution. But if that is impossible, he said the U.S. will respond accordingly. “The options that are at America’s disposal are, you know, they’re familiar to all,” he said.

Given the tepid US response to alleged Iranian military activity in the region, including attacks on civilian shipping in the Persian Gulf and a strike on a US base in Syria, US military action does not seem to be a serious threat. The United States’ bungled pullout from Afghanistan has further eroded American credibility in the region.

“I’m very pessimistic,” said Yoel Guzansky, a former official in the Israeli prime minister’s office who is now a senior fellow at the Institute for National Security Studies in Tel Aviv. “Iran shows patience, resilience, determination. I’m sorry to say the Americans don’t show that, and we don’t have a lot of time.”

What can Israel do?

Israel is not a party to the talks, but it has a huge stake in the outcome.

It considers Iran to be its No. 1 enemy and views a nuclear-armed Iran as an existential threat. Israel is believed to be the only nuclear-armed State in the region, though it does not publicly acknowledge its own arsenal.

Netanyahu’s successor, Naftali Bennett, has been careful not to clash with Biden in public. But his positions are similar to Netanyahu’s. He has expressed hope an improved deal would emerge from the talks but reiterated Israel’s longstanding threat to take unilateral action if necessary.

“We will maintain our freedom to act,” he said last week. On Sunday, he said Israel is “very disturbed” by what he sees as a willingness by the global powers to lift sanctions and reinstate “insufficient restrictions in the nuclear sphere.” He said Israel has been passing this message to all concerned parties.

Despite such threats, Israel might hesitate. Iran has spent the past decade scattering its nuclear sites and hiding them deep underground. Plus, Israel might be reluctant to sabotage a global diplomatic effort.

Is Iran overplaying its hand?

China and Russia, two important Iranian outlets for trade and parties to the deal, could grow impatient with Tehran, especially if a now-shaky system of international nuclear inspections falls apart. Economic pressure continues to squeeze Iranians, who have seen their savings evaporate with the free-fall of the country’s currency.

If talks drag on, the US might turn to new sanctions or even military action. There’s also the risk of a military intervention by Israel.

“We’ll see in the coming days what exactly” Iran’s approach will be, state department spokesman Ned Price said last week. “But we’ve also been very clear that this is not a process that can go on indefinitely.”

With inputs from agencies

 



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Hanukkah 2021: Here's why the Jewish festival of lights is celebrated

People across the world are celebrating the much-loved Jewish holiday Hanukkah, which began yesterday, 28 November,

Prime Minister Narendra Modi marked the occasion by wishing his Israeli counterpart Naftali Bennett and Jewish people around the globe happy Hanukkah, at the beginning of the eight-day festival. He tweeted:

Naftali Bennett, the Prime Minister of Israel thanked PM Modi in reply and wrote that the light of the two nations shines brighter than ever.

External Affairs Minister S Jaishankar also tagged his Israeli counterpart Yair Lapid and wished him happy Hanukkah.

What is Hanukkah?

Hanukkah, based on the Hebrew word for "dedication", is also known as the Festival of Lights. It is celebrated across the world by the Jewish people for eight days, with many considering it the most-beloved Jewish holiday. The festival marks the recovery of Jerusalem and the re-dedication of the Second Temple in Jerusalem.

The eight-day festival is celebrated in the United States as well and is a recognised holiday at the White House. The President of the United States celebrates Hanukkah by hosting annual Menorah lightings and parties.

Celebrations this year:

This year, Hanukkah celebration started on 28 November and will culminate on Monday, 6 December. The date of Hanukkah is determined by the 25th day of the Jewish month of Kislev. The date of the celebration is based on the lunar cycle. The first day of the festival of light can befall anywhere from late November to December on the Gregorian calendar as per the Jewish calendar.

History:

Hanukkah is not mentioned in the Torah, unlike other Jewish holidays. The first five books of the Hebrew Bible are included in the Torah. The festival’s story is mentioned is in the post-biblical Books of the Maccabees.

The festival of lights commemorates the victory of the Maccabees,  a small army of Jewish people which fought against the army of King Antiochus IV of Syria.

The festival is marked by lighting one candle on the menorah (multibranched candelabra) on each night of the festival. A new candle is put in the menorah every night and lit from newest to oldest, with blessings being offered while each candle is lit.



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Sunday, November 28, 2021

Israel shuts borders, US and UK to restrict travel from southern Africa as Omicron variant spooks world

World governments rushed to contain a new, heavily mutated COVID-19 strain Sunday, with Israel slamming its borders shut to foreign nationals and Australia reporting its first cases of the variant.

The variant now known as Omicron has cast doubt on global efforts to fight the pandemic because of fears that it is highly infectious, forcing countries to reimpose measures many had hoped were a thing of the past.

Scientists are racing to determine the threat posed by the heavily mutated strain, particularly whether it can evade existing vaccines.

Several countries have also announced plans to restrict travel from southern Africa, where it was first detected, including key travel hub Qatar, the United States, Britain, Saudi Arabia, Kuwait and the Netherlands.

The strictest among them is Israel, which said Sunday it would close its borders to all foreigners in a bid to curb the spread of the variant, just four weeks after reopening to tourists after a prolonged closure due to COVID.

"We are raising a red flag," Israeli Prime Minister Naftali Bennett said, adding the country would order 10 million PCR test kits to stem the "very dangerous" strain.

Israeli citizens will be required to present a negative PCR test and quarantine for three days if they have been vaccinated against the coronavirus and seven days if they have not, the prime minister's office said.

But the virus strain has already slipped through the net, and has now been found everywhere from the Netherlands to Hong Kong and Australia, where authorities Sunday said they had detected it for the first time in two passengers from southern Africa who were tested after flying into Sydney.

The arrival of the new variant comes just a month after Australia lifted a ban on citizens travelling overseas without permission, with the country's border also set to open to skilled workers and international students by the year's end.

Both cases were fully vaccinated, authorities said, and landed the same day that Canberra announced a sweeping ban on flights from nine southern African countries, including South Africa and Zimbabwe.

The speed at which governments slammed their borders shut took many by surprise, with travellers thronging Johannesburg international airport, desperate to squeeze onto the last flights to countries that had imposed sudden travel bans.

In the Netherlands, 61 passengers tested positive after arriving on two flights from South Africa in an ordeal one passenger described as "Dystopia Central Airline Hallway".

The New York Times global health reporter Stephanie Nolen said passengers, including babies and toddlers, were crammed together waiting to get tested, while "still 30 percent of people are wearing no mask or only over mouth".

'Blame game'

Scientists in South Africa last week said that they had detected the new B.1.1.529 variant with at least 10 mutations, compared with three for Beta or two for Delta -- the strain that hit the global recovery hard and sent millions worldwide back into lockdown.

The variant has also revived geopolitical fault lines exacerbated by the pandemic, with the US quick to hail South Africa's openness about the new strain, a thinly-veiled jab at China's handling of information about the original outbreak.

Secretary of State Antony Blinken Saturday "praised South Africa's scientists for the quick identification of the Omicron variant and South Africa's government for its transparency in sharing this information, which should serve as a model for the world", a state department statement said.

But South Africa has complained it is being unfairly hit with "draconian" air travel bans for having first detected the strain, which the World Health Organization has termed a "variant of concern".

"Excellent science should be applauded and not punished," its foreign ministry said in a statement.

UK to enforce new Covid rules from Tuesday

Meanwhile, Britain's government on Sunday defended the pace and scale of its response to the new Omicron strain of COVID-19 against criticism that it was again falling behind the curve.

Health secretary Sajid Javid said mandatory mask-wearing will return to shops and public transport in England on Tuesday, and told families to plan for Christmas "as normal", despite new rules to combat the Omicron variant.

Also from Tuesday, all passengers arriving in Britain are being instructed to take a PCR test for Covid-19, and self-isolate until they register negative.

Prime Minister Boris Johnson had announced the tougher measures at a hastily arranged news conference on Saturday, but did not specify when they would take effect.

Johnson and other senior conservatives were widely criticised for his travel and quarantine policy earlier in the pandemic, when he kept borders open to foreign travellers even as infection rates spiralled, yielding Britain one of the world's worst per-capita death tolls from COVID.

The government controversially dropped the masks mandate in July for England, after a prior lockdown, but the devolved administrations in Scotland, Wales and Northern Ireland had kept it in place.

All four UK nations are expected to adopt the same PCR rule, after England again diverged in July by requiring only a simple lateral flow test for incoming passengers on flights, ships and trains.

Travel from 10 countries in southern Africa is now banned because of Omicron, but Javid conceded that hundreds of passengers had arrived on flights from South Africa on Friday without being tested.

But he told BBC television: "I think the speed at which we acted at could not have been any faster."

'Holes in the defences'

Javid ruled out reintroducing social distancing rules and work-from-home guidance, which were also controversially discarded in England earlier this year against the advice of government scientists.

Javid said it was too early to judge the effectiveness of existing vaccines against Omicron, as drugs manufacturers rush to research new treatments against the emergent strain.

But the government is seeking approval from its Joint Committee on Vaccination and Immunisation (JCVI) to expand the rollout of booster jabs, shortening the time-frame between second and third shots, and broadening the age range to all over-18s.

The JCVI is expected to respond early next week, Javid said.

He added that no further cases of Omicron had been detected in Britain, after the government on Saturday confirmed the first two cases, both linked to travel from southern Africa.

The Opposition Labour party said the government was again doing too little, too late after Omicron emerged.

Even after Tuesday, passengers can enter Britain without a pre-departure test and travel freely from their port of entry on public transport, Labour's foreign affairs spokeswoman Lisa Nandy said.

"We desperately want to see them tighten up the travel restrictions," she said on Sky News.

"There is a real problem when for 18 months the government has been warned that there are holes in those defences and still hasn't taken action to plug (them)."

Dutch find 13 new COVID variant cases among RSA passengers

Dutch health authorities said on Sunday they had found at least 13 cases of the new Omicron strain among 61 quarantined passengers who tested positive for coronavirus after arriving from South Africa. "The Omicron variant has so far been identified in 13 of the positive tests. The investigation has not yet been completed. The new variant may be found in more test samples," the National Institute for Public Health (RIVM) said in a statement.

Dutch authorities began testing for the Omicron variant after 61 out of 600 passengers on board two flights from South Africa to Amsterdam on Friday tested positive for COVID-19. Health minister Hugo de Jonge made an "urgent request" to people returning from southern Africa to get tested for Covid "as soon as possible".

"It is not unthinkable that there are more cases in the Netherlands," De Jonge told reporters. "Yes, we are concerned. But how much we don't know yet."

The minister added: "What is important now is that we keep our finger on the pulse, and keep up with the sequencing" of COVID tests to look for the new variant.

The positive cases are being kept in quarantine at a hotel near Amsterdam's Schiphol Airport.

Swiss voters back COVID-19 pass law

Also on Sunday, Swiss voters have firmly backed the law behind the country's COVID pass, according to projections following Sunday's referendum after an unusually tense and hostile campaign.

Shortly after the polls closed at noon (1100 GMT), market researchers GFS Bern, who conducted the main polling throughout the campaign, projected that 63 percent of voters had backed the "yes" vote.

The law provides the legal basis for the so-called COVID certificate, indicating that a person has been vaccinated or has recovered from the disease.

Opponents have said the certificate, which has been required since September for access to restaurants and other indoor spaces and activities, is creating an "apartheid" system.

As in much of Europe, Switzerland has seen growing anger over restrictions aimed at reining in the pandemic, and pressure to get vaccinated.

But in a country where referendums take place every few months in a climate of civility and measured debate, the soaring tensions around the vote came as a shock.

Police upped security around several politicians who have faced a flood of insults and even death threats.

In anticipation of protests at the results, police have fenced off the seat of government and parliament in Bern.

Observers warned that Sunday's vote could exacerbate tensions, and even spark a violent backlash from the losing side.

The campaign saw repeated protests, often led by the so-called "Freiheitstrychler", or "Freedom ringers" -- men dressed in white shirts embroidered with edelweiss flowers and with two large cowbells suspended from a yoke resting on their shoulders.

Some of the demonstrations led to violent clashes with police, who used rubber bullets and tear gas to rein in the crowds.

The referendum came as the worrying new COVID-19 variant Omicron, first detected in southern Africa and classified as a variant of concern by the World Health Organisation, has rattled countries and markets around the world.

Australia detects first Covid Omicron infections

Health officials said Sunday they had detected the Covid Omicron strain in Australia for the first time in two passengers who were tested after flying into Sydney from southern Africa.

The eastern state of New South Wales' health authority said it had conducted urgent genomic testing and confirmed the new strain was present in the two people who landed in Sydney on Saturday.

Both passengers came from southern Africa and arrived in Australia on a Qatar Airways flight via Doha, NSW Health said in a statement.
They tested positive for Covid shortly after arriving, leading to an urgent analysis for possible infection by the heavily mutated Omicron strain.

"The two positive cases, who were asymptomatic, are in isolation in the special health accommodation. Both people are fully vaccinated," NSW Health said.

Another 12 passengers from southern Africa on the same flight did not test positive for Covid but had been placed in quarantine, it said.
About 260 passengers and crew on the plane have also been told to isolate, the health authority said.

The plane with the infected passengers landed on the same day that Australia announced it was banning flights from nine southern African countries including South Africa and Zimbabwe.

The World Health Organization has listed Omicron as a variant of concern and said it could take several weeks to know if there are significant changes in transmissibility, severity or implications for Covid vaccines, tests and treatments.

'Get vaccinated':

The arrival of the new variant comes just a month after Australia lifted a ban on citizens travelling overseas without permission, with the country's border also set to open to skilled workers and international students by year's end.

After more than 18 months of closed borders, fully vaccinated Australian citizens no longer have to seek an exemption to leave the country. On 20 March last year Australia introduced some of the world's toughest border restrictions in response to the coronavirus pandemic.
For almost 600 days, countless international flights were grounded, and overseas travel slowed to a trickle.

Quarantine arrangements for returning vaccinated residents depend on where they arrive in Australia. While Sydney has scrapped quarantine for returning travellers, other Australian states with lower vaccination rates still have mandatory and costly 14-day hotel quarantine requirements.

It is unclear whether the arrival of the new variant will lead to a return to tighter rules. Speaking a few hours before the confirmation that the Omicron strain had arrived in Australia, New South Wales Premier Dominic Perrottet seemed reluctant to commit to any new restrictions.

"We need to learn to live alongside the virus and also live alongside the various strains of the virus that will come our way," Perrottet said. "The best thing that we can do is to get vaccinated and get booster shots," he added. "There are limits to what the state and federal government can do."

Angola shuts borders to regional neighbours over Omicron

Angola has become the first southern African country to suspend flights from its regional neighbours in a bid to prevent the spread of the Omicron variant of the coronvirus, its national airline said.

A long list of countries have shut their borders to the region since South African scientists announced the new coronavirus variant last week.
Angola's state-owned TAAG airline on Saturday said it would suspend all flights to Mozambique, Namibia and South Africa from Sunday until further notice.

The suspension is in compliance with the government's decision to temporarily ban air links to Botswana, Eswatini, Lesotho, Mozambique, Namibia, South Africa and Zimbabwe, it said in a statement.

Angola itself was placed on the UK's red travel list over concerns about Omicron last week.

Known as B.1.1.529, South African scientists announced its discovery on November 25, blaming it for a resurgence in cases in the continent's worst-hit country.

With multiple mutations, Omicron is thought to be highly contagious and resistant to immunity, although its ability to evade vaccines is still being assessed.

The World Health Organisation has designated it a variant of concern.

While many Western and Asian countries rushed to enforce travel bans, most African nations have kept their borders open for the time being.

Angola is one a few to have shut doors, along with Mauritius, Morocco and the Seychelles.

With inputs from agencies



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Omicron: Five steps to avoid, ten to take immediately

South Africa reacted with outrage to travel bans, first triggered by the UK, imposed on it in the wake of the news that its genomics surveillance team had detected a new variant of the SARS-CoV-2 virus. The Network for Genomics Surveillance in South Africa has been monitoring changes in SARS-CoV-2 since the pandemic first broke out.

The new variant – identified as B.1.1.529 has been declared a variant of concern by the World Health Organisation and assigned the name Omicron.

The mutations identified in Omicron provide theoretical concerns that the variant could be slightly more transmissible than the Delta variant and have reduced sensitivity to antibody activity induced by past infection or vaccines compared to how well the antibody neutralises ancestry virus.

As vaccines differ in the magnitude of neutralising antibody induced, the extent to which vaccines are compromised in preventing infections due to Omicron will likely differ, as was the case for the Beta variant.

However, as vaccines also induce a T-cell response against a diverse set of epitopes, which appears to be important for prevention of severe COVID, it is likely that they would still provide comparable protection against severe COVID due to Omicron compared with other variants.

The same was observed for the AstraZeneca vaccine. Despite not protecting against the mild-moderate Beta COVID in South Africa, it still showed high levels of protection (80 percent effective) against hospitalisation due to the Beta and Gamma variants in Canada.

In view of the new variant, there are a few steps that governments shouldn’t be taking. And some they should be taking.

What not to do

Firstly, don’t indiscriminately impose further restrictions, except on indoor gatherings. It was unsuccessful in reducing infections over the past three waves in South Africa, considering 60 percent-80 percent people were infected by the virus based on sero-surveys and modelling data. At best, the economically damaging restrictions only spread out the period of time over which the infections took place by about 2-3 weeks.

This is unsurprising in the South African context, where ability to adhere to the high levels of restrictions are impractical for the majority of the population and adherence is generally poor.

Secondly, don’t have domestic (or international) travel bans. The virus will disseminate irrespective of this – as has been the case in the past. It’s naive to believe that imposing travel bans on a handful of countries will stop the import of a variant. This virus will disperse across the globe unless you are an island nation that shuts off the rest of the world.

The absence of reporting of the variants from countries that have limited sequencing capacity does not infer absence of the variant. Furthermore, unless travel bans are imposed on all other nations that still allow travel with the “red-listed” countries, the variant will directly or indirectly still end up in countries imposing selective travel bans, albeit perhaps delaying it slightly.

In addition, by the time the ban has been imposed, the variant will likely have already been spread. This is already evident from cases of Omicron being reported from Belgium in a person with no links to contact with someone from Southern Africa, as well as cases in Israel, UK and Germany.

All travel bans accomplish in countries with selective red-listed countries is delay the inevitable. More could possibly be accomplished by rigorous exit and entry screening programmes to identify potential cases and mandating vaccination.

Third, don’t announce regulations that are not implementable or enforceable in the local context. And don’t pretend that people adhere to them. This includes banning alcohol sales, whilst being unable to effectively police the black market.

Fourth, don’t delay and create hurdles to boosting high risk individuals. The government should be targeting adults older than 65 with an additional dose of the Pfizer vaccine after they’ve had two shots. The same thing goes for other risk groups such as people with kidney transplants, or people with cancer and on chemotherapy, people with any other sort of underlying immuno-suppressive condition.

South Africa shouldn’t be ignoring World Health Organisation’s guidance which recommends booster doses of high risk groups. It should de-prioritise, for the time being, vaccinating young children with a single dose.

Fifth, stop selling the herd immunity concept. It’s not going to materialise and paradoxically undermines vaccine confidence. The first generation vaccines are highly effective in protecting against severe COVID-19, but less predictable in protecting against infection and mild COVID due to waning of antibody and ongoing mutations of the virus. Vaccination still reduces transmission modestly, which remains of great value, but is unlikely to lead to “herd-immunity” in our lifetimes.

Instead we should be talking about how to adapt and learn to live with the virus.

There is also a list of things that should be considered in the wake of the Omicron variant, irrespective of whether it displaces the Delta variant (which remains unknown).

What to do

Firstly, ensure health care facilities are prepared, not only on paper – but actually resourced with staff, personal protective equipment and oxygen, etc.

There are 2,000 interns and community service doctors in South Africa waiting for their 2022 placement confirmation. We cannot once again be found wanting with under-prepared health facilities.

Provide booster doses of J&J or Pfizer to all adults who received a single dose J&J. It’s needed to increase protection against severe COVID. A single dose of the J&J vaccine reduced hospitalisation due to Delta variant in South Africa by 62 percent in South African healthcare workers, whereas two doses of AZ and mRNA vaccines in general had greater than 80 percent-90 percent protection against severe disease from the Delta variant.

Studies confirm a two dose schedule of the Johnson & Johnson vaccine is superior in protecting against hospitalisation than a single dose. And if you want durability of protection, you need to boost, which can be done with another dose of Johnson & Johnson or a dose of mRNA vaccine.

The evidence is clear that the type of immune responses from a heterologous approach of AZ or JJ followed by a mRNA vaccines such as Pfizer/Biontech induces superior neutralising and cell mediated immune responses than two doses of the non-replicating vector vaccines.

Thirdly, implement vaccine passports for entry into any indoor space where others gather, including places of worship and public transport. Vaccination might be a choice currently, however, choices come with consequences. Even if vaccines only reduce transmission modestly, over and above the infections they prevent, a breakthrough case in a vaccinated individual poses less risk of transmission to others than infection in an unvaccinated and previously uninfected individual.

Fourth, continue efforts at reaching out to the unvaccinated and under-immunised. This should include the use of pop up facilities where people are likely to gather and other targeted community outreach programs.

Fifth, immediately boost high risk groups older than 65 and others who have immunosuppressive conditions. The primary goal of vaccination therefore needs to be on reducing severe disease and death. This requires targeted strategies on who to prioritise.

Sixth, encourage responsible behaviour to avoid re-imposing alcohol and other restrictions to punish all due to irresponsibility on part of a minority.

Seventh, monitor bed availability at regional level to help decide on regional action to avoid overwhelming of facilities. Higher levels of restrictions need to be tailored for when we expect overwhelming of health facilities. As hospitalisation usually lag behind community infection rates by 2-3 weeks, keeping an eye on case rates and hospitalization rates could predict which facilities in which regions may come under threat.

This would allow for a more focused approach to imposing restrictions to relieve anticipated pressure on health facilities 2-3 weeks before expected. This will not change the total number of hospitalisations. But it will spread it out over a longer period of time and make it more manageable.

Eighth, learn to live with the virus, and take a holistic view on the direct and indirect effects of the pandemic on livelihoods. The detrimental indirect economic, societal, educational, mental health and other health effects of a sledge-hammer approach to dealing with the ongoing pandemic threatens to outstrip the direct effect of COVID in South Africa.

Ninth, follow the science and don’t distort it for political expediency.

Tenth, learn from mistakes of the past, and be bold in the next steps.The Conversation

Shabir A Madhi, Dean Faculty of Health Sciences and Professor of Vaccinology at University of the Witwatersrand; and Director of the SAMRC Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand

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